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Postdoctoral Fellow in Cell Biology and Cancer Therapies

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A postdoctoral fellow opening in Cell Biology and Cancer Therapies (Anticancer Drugs) is available at the University of Waterloo in Canada.  Our research team focuses on a new perspective on the molecular-mechanism of drug action to develop novel drugs for high performance cancer treatment.  We have applied state-of-the-art femtobiology/femtomedicine technology for the studies of molecular mechanisms of anticancer drugs and for development of new effective drugs for cancer therapies, including radiotherapy, chemotherapy and photodynamic therapy. We combine our novel femtosecond time-resolved laser spectroscopy with molecular biology and cell biology methods for assessing DNA strand breaks / fragmentation, cell cycle, and cell death (viability, clonogenic and apoptosis) assays.  We have our unique techniques to discover the molecular pathways regulating DNA damage and cell death.  Our projects also aim to continue our exploration of new exciting frontiers in the transdisciplinary fields of femtobiology and femtomedicine and to integrate the novel femtobiology/femtomedicine technology in Waterloo with the Radiation Medicine Program of the Princess Margaret Hospital/MaRS in Toronto.  This collaboration provides an ideal vehicle to bring innovations arising from studies in femtobiology to clinical formulation and evaluation.

The candidates for postdoctoral positions must have a PhD in one or more of the fields of cell biology, molecular biology, medical biochemistry and biophysics, and is familiar with cell biology and molecular biology techniques. Experience with quantitative DNA damage and cell death assays (in vitro, cell-culture level, in vivo measurements) and animal cancer models will be an asset. The candidates should have an excellent academic record or track record of original research, and the ability to work in a team environment.

Submit application to Prof. Qing-Bin Lu, Email: qblu@uwaterloo.ca.

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